FDA-cleared profile

Jazz

AI Medical AG

Jazz semi-automatically labels, visualizes, and quantifies segmentable brain structures on MR for patients with known multiple sclerosis and/or brain metastasis, with physician-reviewed/correctable annotations and radiological report output.

Evidence status: each field states its source quality, applicability, and review date. Research pending, information not established, and vendor documentation pending remain distinct outcomes.

Clinical details

What this tool is for

Start with the authorized purpose, then verify how it fits your service line and reading workflow.

Exact purpose
Jazz semi-automatically labels, visualizes, and quantifies segmentable brain structures on MR for patients with known multiple sclerosis and/or brain metastasis, with physician-reviewed/correctable annotations and radiological report output.
  • FDA source
  • Exact FDA submission
  • Checked 2026-09-07
Intended users
Trained physicians, including neuroradiologists, who review and control the annotations and report output.
  • FDA source
  • Exact FDA submission
  • Checked 2026-09-07
Care setting and population
Hospitals, imaging centers, and image-processing laboratories for patients with known multiple sclerosis and/or brain metastasis.
  • FDA source
  • Exact FDA submission
  • Checked 2026-09-07
Workflow role
Semi-automatic brain segmentation, lesion/structure quantification, and radiological report support
  • FDA source
  • Exact FDA submission
  • Checked 2026-09-07
Required input
MR brain images from patients with known multiple sclerosis and/or brain metastasis; preprocessing coregisters images, recognizes contrast, and may pre-annotate abnormalities.
  • FDA source
  • Exact FDA submission
  • Checked 2026-09-07
Output and human action
Physician-reviewed labels, visualizations, volumetric measurements, lesion counts/volumes, and an electronic radiological report saved in a user-selected txt, PDF, or DICOM format; the physician may accept, correct, discard, or manually create annotations.
  • FDA source
  • Exact FDA submission
  • Checked 2026-09-07
Limitations
Every pre-annotation and report requires physician review; the exact indication is limited to patients with a known diagnosis of multiple sclerosis and/or brain metastasis; the reviewed packet does not establish use as a general screening or diagnostic substitute.
  • FDA source
  • Exact FDA submission
  • Checked 2026-09-07

Regulatory identity

FDA record and catalog context

The FDA listing establishes the regulatory identity. It does not by itself establish local workflow fit, pricing, security, or performance in your environment.

FDA submission
K223659
  • FDA source
  • Exact FDA submission
  • Checked 2026-08-31
Modality
MRI
  • FDA source
  • Exact FDA submission
  • Checked 2026-09-07
Anatomy
Brain
  • FDA source
  • Exact FDA submission
  • Checked 2026-09-07
Clearance type
510(k)
  • FDA source
  • Exact FDA submission
  • Checked 2026-08-31
Decision date
2023-09-22
  • FDA source
  • Exact FDA submission
  • Checked 2026-08-31
FDA status
FDA-cleared
  • FDA source
  • Exact FDA submission
  • Checked 2026-08-31

Implementation

Questions for IT, informatics, and operations

Use these fields to structure a vendor demo, security review, and implementation estimate.

Integration
The FDA comparison describes DICOM-compatible input/output, off-the-shelf hardware, and use by trained professionals in hospitals, imaging centers, or image-processing labs; exact local interface and routing configuration require confirmation.
  • FDA source
  • Exact FDA submission
  • Checked 2026-09-07
Deployment and data flow
Vendor documentation pending
  • Vendor confirmation
  • Exact FDA submission
  • Checked 2026-09-07

The exact packet establishes off-the-shelf hardware compatibility but does not establish a current cloud, on-premise, or hosting-region deployment model.

Security and privacy
Vendor documentation pending
  • Vendor confirmation
  • Exact FDA submission
  • Checked 2026-09-07

The reviewed sources do not establish a scoped security audit, certification, or control set.

Training and support
Vendor documentation pending
  • Vendor confirmation
  • Exact FDA submission
  • Checked 2026-09-07

Training, credentialing, and implementation support terms were not established.

Monitoring and change control
Vendor documentation pending
  • Vendor confirmation
  • Exact FDA submission
  • Checked 2026-09-07

Current post-deployment monitoring and change-control practices were not established.

DICOM-compatible physician-controlled reporting

The exact submission supports DICOM-compatible MR workflow, physician review/correction of pre-annotations, and user-selected txt, PDF, or DICOM report/image output.

exact submission · checked 2026-09-07

Current Jazz lesion-tracking workflow

AI Medical's official Jazz page describes single-click annotation, automatic report generation, longitudinal lesion re-identification, and quantitative follow-up views; the current page is family context and is not used to assign exact K223659 performance or deployment.

product family · checked 2026-09-07

Current family workflow context only; exact-version compatibility requires confirmation.

Evidence

Performance evidence

Metrics are shown only when they are tied to a source, endpoint, population, and tested product version. Candidate literature without exact product and version linkage is not shown as product evidence.

Evidence summary
FDA performance testing used 344 subject datasets including healthy, multiple sclerosis, and metastasis patients; measured volumes were compared with manually labeled ground truth, reproducibility used test-retest data, and all reported acceptance criteria passed.
  • FDA source
  • Exact FDA submission
  • Checked 2026-09-07
Reported sensitivity
40%
  • FDA source
  • Exact FDA submission
  • Checked 2026-08-13

Values reported in the exact-submission materials. Consult the linked source for endpoint, threshold, population, and confidence interval before comparison.

Reported specificity
40%; 50%
  • FDA source
  • Exact FDA submission
  • Checked 2026-08-13

Values reported in the exact-submission materials. Consult the linked source for endpoint, threshold, population, and confidence interval before comparison.

No contextualized exact-version metric has completed evidence review. Regulatory-document values, when available, are shown above with their limitations.

Jazz accuracy and reproducibility validation

  • DesignRetrospective accuracy and test-retest reproducibility validation against manually labeled ground truth
  • Population344 subject datasets including healthy subjects, multiple sclerosis patients, and metastasis patients.
  • Scopeexact submission
  • Tested versionJazz submitted in K223659; build not stated
  • Samplen=344
  • IndependenceIndependence not established

K223659

The FDA reports that all predefined acceptance criteria passed, but the summary provides thresholds rather than observed sensitivity, specificity, Dice, or reproducibility estimates. Training images were segregated from the test set; independent investigators or sponsorship were not established.

Costs and setup

Budget and ongoing governance

These are common procurement questions; unknown values remain visible until a source supports them.

Pricing and total cost
Vendor documentation pending
  • Vendor confirmation
  • Exact FDA submission
  • Checked 2026-09-07

No public amount, range, currency, geography, or contract term was established.

Reimbursement and coding
Research pending
  • Needs research
  • Exact FDA submission
  • Checked 2026-09-07

No payer or CMS policy review was performed in this worker cohort.

Safety and lifecycle

Postmarket record

Recall and adverse-event records are shown only after product matching. Adverse-event reports do not establish incidence or causality.

Postmarket safety review
Not established in reviewed sources
  • Reviewed sources checked
  • Exact FDA submission
  • Checked 2026-09-04

No native submission-identifier match was found in the checked openFDA radiology recall snapshot. Product-name, manufacturer, and adverse-event searches remain necessary; this does not establish that no recall or safety report exists.

Buyer worksheet

Open questions to take to the vendor

Open evaluation checklist

Research record

What has been checked

This audit distinguishes completed source review from fields that have not yet been researched.

Human reviewedStatus
2026-09-07Last searched
26Fields reviewed
10Source classes checked
20Screened PubMed leads
10Screened trial leads
0Unreviewed FDA recall leads

The stored PubMed, ClinicalTrials.gov, and exact-submission recall metadata candidates were screened by identifier and count. The records were not treated as a full paper, trial, or postmarket review. The current discovery snapshot contains 20 PubMed and 10 ClinicalTrials.gov candidate records; its dated, count-matched human screening remains current. Unlinked candidates remain quarantined. Native FDA recall identifiers produced 0 postmarket candidate records; 0 have been reviewed (0 published, 0 rejected) and 0 remain unreviewed.

Candidate leads were screened against the exact product and tested version. Unlinked records remain quarantined.

Source classes: fda ai list, fda decision summary, acr ai central product, vendor product page, literature index, trial registry, fda device recall, pubmed, clinical trials, openfda device recall

Sources & history

How this profile was documented

Open the ledger for source dates, scope, and research-record updates.

View source ledger and history

Source ledger

  1. FDA 510(k) K223659: Jazz

    U.S. Food and Drug Administration - Published 2023-09-22 - Accessed 2026-09-07

    Scope: identity, clinicalUse, modality, anatomy, workflow, evidence, implementation

  2. Artificial Intelligence-Enabled Medical Devices

    U.S. Food and Drug Administration - Accessed 2026-08-31

    Scope: regulatoryIdentity, modalityContext

  3. Jazz model card (K223659)

    American College of Radiology - Published 2026-08-17 - Accessed 2026-09-01

    Scope: purpose, modality, intendedUsers, output, limitations, integration, anatomy, evidenceStudies, implementationCapabilities

  4. PubMed biomedical literature index

    U.S. National Library of Medicine - Accessed 2026-09-01

    Scope: evidenceDiscovery

  5. ClinicalTrials.gov study registry

    U.S. National Library of Medicine - Accessed 2026-09-01

    Scope: evidenceDiscovery, studyStatus

  6. openFDA Device Recall API

    U.S. Food and Drug Administration - Accessed 2026-09-02

    Scope: recallDiscovery, nativeSubmissionMatching

  7. Jazz medical image analysis software

    AI Medical AG - Accessed 2026-09-08

    Scope: productFamily, clinicalWorkflow, implementationCapabilities

Research history

  1. K223659 FDA decision

    Regulatory record

    510(k)

  2. Source-review record updated

    Research record

    human reviewed

Alternatives

Related tools to compare

FDA-cleared K261405

ANDI 2.2

Imeka Solutions, Inc.

ANDI 2.2 processes brain MR images for atlas-assisted visualization, segmentation and volumetric quantification, presenting adjunctive DICOM-readable information for trained...

Modality
MRI
Anatomy
Brain
Decision
2026-05-28
FDA-cleared K260032

Morph

BeauBrain Healthcare, Inc.

Morph automatically labels, visualizes, and volumetrically quantifies segmentable brain structures from MR images and may compare measurements with reference percentile data; it...

Modality
MRI
Anatomy
Brain
Decision
2026-05-13
FDA-cleared K253057

AI-Rad Companion Brain MR

Siemens Healthcare GmbH

Brain MRI morphometry and white matter hyperintensity quantification, including normative comparison and longitudinal change assessment for clinician review.

Modality
MRI
Anatomy
Brain
Decision
2026-01-22
FDA-cleared K252298

ANDI 2.0

Imeka Solutions, Inc.

Adjunctive quantitative brain MRI analysis that compares patient measures with normative and longitudinal references; a physician reviews all results and makes the clinical...

Modality
MRI
Anatomy
Brain
Decision
2025-10-22